MR3 Network Members

The Rehabilitation Research Resource to Enhance Clinical Trials (REACT) Center serves as a national resource for the medical rehabilitation research community providing the knowledge, skills, and tools needed to catalyze high-impact, interdisciplinary clinical trials. The center can help investigators successfully design and conduct clinical trials that can fill key gaps in medical rehabilitation and thereby optimize patient care. The Center also funds pilot studies and provides education, collaboration, data sharing, consultative services, and access to core facilities to the national research community; all with the goal of fostering innovative clinical and translational research and, ultimately, definitive clinical trials.

Marcas Bamman, Ph.D., Principal Investigator
The University of Alabama at Birmingham (with Baylor College of Medicine).
NIH grant P2CHD086851

AR3T logo

The Alliance for Regenerative Rehabilitation Research & Training (AR3T) works to expand scientific knowledge, expertise and methodologies across the domains of rehabilitation science and regenerative medicine. Regenerative rehabilitation is the integration of principles and approaches from these two domains: 1) regenerative medicine, which focuses on the repair or replacement of tissue lost to injury, disease, or age, primarily via the enhancement of endogenous stem cell function or the transplantation of exogenous stem cells, and 2) rehabilitation science, which focuses on mechanical and other physical stimuli to promote functional recovery. Creating synergies through the integration of these two approaches with the ultimate goal of optimizing independence and participation of individuals with disabilities is the ultimate goal of AR3T.

Fabrisia Ambrosio, PhD, MPT, University of Pittsburgh, Principal Investigator
Thomas Rando, M.D., Ph.D., Stanford University, Principal Investigator
University of Pittsburgh and Stanford University (with Mayo Clinic and The University of California, San Francisco)
NIH grant P2CHD086843

NCSRR logo

The National Center for Simulation in Rehabilitation Research (NCSRR) works to equip the rehabilitation research community with state-of-the-art simulation tools, enabling investigators to complement experimental studies of human performance with advanced simulation software and biomechanical models. The center's freely available simulation tool, OpenSim, is already used by hundreds of research teams around the world to advance rehabilitation science.

Scott L. Delp, Ph.D., Principal Investigator
Stanford University
NIH grants R24HD065690 and P2CHD065690

TREAT logo

Translation of Rehabilitation Engineering Advances and Technology (TREAT) is a collaborative consortium that provides tailored experiential learning programs have been created to help innovators navigate the challenging commercialization process. The collective expertise of our team, member organizations, and collaborating institutions is leveraged to provide early stage product evaluation, technology assessment, prototype development, commercialization planning and execution, and to develop and foster a pragmatic approach to conducting comparative effectiveness clinical trials.

Richard Greenwald, Ph.D., Principal Investigator
Jonathan D. Lurie, M.D., M.S., Principal Investigator
Simbex (with The Dartmouth Institute, Thayer School of Engineering at Dartmouth College, and Boston University)
NIH grants R24HD065703 and P2CHD086841


The National Center of Neuromodulation for Rehabilitation (NC NM4R) supports researchers and clinicians who are currently working in the field of neuromodulation for rehabilitation and who are interested in gaining immediate knowledge and training in cutting edge and next generation NM4R applications. These applications allow us to study neuroplastic changes associated with brain stimulation and operant conditioning and help understand mechanisms of neuroplasticity and will help members develop new rehabilitation interventions. Members of the NM4R community are eligible to attend workshops and conferences in neuromodulation, access webinars and saved presentations, apply for pilot project funding, and collaborate with other members of the community. Additionally, members will be given access to our extensive research data base to further enhance their research and practice.

Steven Kautz, Ph.D., Principal Investigator
Medical University of South Carolina
NIH grant P2CHD086844

CLDR logo

The Center for Large Data Research and Data Sharing in Rehabilitation (CLDR) supports the development of knowledge and rehabilitation research capacity by increasing the quantity and quality of rehabilitation outcomes research using large administrative and research datasets. The center's current focus is on data sharing and archiving information from completed rehabilitation research studies, with a long-term goal of helping to create a research environment and culture where rehabilitation scientists will have the skills and knowledge to become significant contributors to the changes in health care policy and practice that are being driven through the use of large data and the unprecedented expansion of health care information that has occurred in recent years.

Kenneth Ottenbacher, Ph.D., OTR, Principal Investigator
The University of Texas Medical Branch, Galveston (with Cornell University and the University of Michigan)
NIH grant P2CHD065702

The University of Alabama at Birmingham
1313 13th Street South, OSB 3rd Floor
Birmingham, AL 35205
Telephone: (205) 996-0832

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