The National Institute of Child Health and Human Development (NICHD), through the National Center for Medical Rehabilitation Research (NCMRR), the National Institute for Neurological Disorders and Stroke (NINDS), and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have funded six P2C resource center grants that provide infrastructure and access to expertise, technologies, and resources to support clinical and translational research in medical rehabilitation across a wide range of disciplines and disease focus areas.

Network Sites

National Rehabilitation Research Resource To Enhance Clinical Trials (REACT)
Marcas Bamman, PhD, Principal Investigator
The University of Alabama at Birmingham (with Baylor College of Medicine) NIH grant P2CHD086851

Alliance for Regenerative Rehabilitation Research & Training (AR3T)
Michael Boninger, MD, University of Pittsburgh, Principal Investigator
Thomas Rando, MD, PHD, Stanford University, Principal Investigator
University of Pittsburgh (with Mayo Clinic, Stanford University, and The University of California, San Francisco) NIH grant P2CHD086843

National Center for Simulation in Rehabilitation Research (NCSRR)
Scott L. Delp, PhD, Principal Investigator
Stanford University NIH grants R24HD065690 and P2CHD065690

Translation of Rehabilitation Engineering Advances and Technology (TREAT)
Richard Greenwald, PhD, Principal Investigator
Jonathan D. Lurie, MD, MS, Principal Investigator

Simbex (with The Dartmouth Institute, Thayer School of Engineering at Dartmouth College, and Boston University) NIH grants R24HD065703 and P2CHD086841

National Center of Neuromodulation for Rehabilitation (NM4R)
Steven Kautz, PhD, Principal Investigator
Medical University of South Carolina NIH grant P2CHD086844

Center for Large Data Research and Data Sharing in Rehabilitation (CLDR)
Kenneth Ottenbacher, PhD, OTR, Principal Investigator
The University of Texas Medical Branch, Galveston (with Cornell University and the University of Michigan) NIH grant P2CHD065702

News and Funding Opportunities

Request for Information (RFI): Input on a Planned NIH Common Fund Mechanisms of Fatigue Program

Responses accepted until July 28, 2016

The purpose of this RFI is to solicit background information and guidance on the development of various research directions of the planned NIH Common Fund Mechanisms of Fatigue program. The goals of this program would be to determine whether molecular, cellular, or imaging signatures of fatigue can be defined; if so, the program would identify molecular triggers of fatigue and determine how this condition is resolved by rest in healthy individuals. This would then provide the foundation necessary to understand why fatigue can be debilitating and/or fails to resolve in the presence of disease/disorders/aging. Data from these studies would be made available in a public database and would be expected to catalyze research in this area for years to come. Learn more and respond.

CMDRB Psychological Health (PH)/Traumatic Brain Injury (TBI) Research Program - Complex Traumatic Brain Injury Rehabilitation Research Award

Preapplication deadline: August 17, 2016

The FY16 PH/TBIRP Complex TBI Rehabilitation Research Award (CTRRA) is intended to support observational studies and clinical trials addressing rehabilitation of patients with complex TBI. TBI is defined as being caused by (1) a direct blow or impact to the head, (2) a penetrating head injury, or (3) an exposure to external forces such as blast waves that disrupt the function of the brain. Not all blows to the head or exposure to external forces result in a TBI. The severity of TBI may range from “mild” — a brief change in mental status or consciousness — to “severe,” an extended period of unconsciousness or confusion after the injury. Learn more and apply.

TREAT Pilot Project Funding Opportunity

Pilot grant applications due: September 30, 2016

The Center for Translation of Rehabilitation Engineering Advances and Technology (TREAT) offers Pilot Project grants support the development and commercialization of novel rehabilitation and assistive technology ideas. Innovators from all professional backgrounds are encouraged to submit proposals for competitive review. Learn more and apply.

Funding Opportunity Announcement (FOA): Predictors and Determinants of Age-Related Changes in Resiliencies to Physical Stressors in Humans (UH2/UH3) (RFA-AG-17-014)

Application deadline: November 3, 2016, by 5:00 PM local time of applicant organization.

This FOA from the National Institute on Aging is a phased innovation initiative to enhance clinical tools to assess resiliencies and advance our understanding of age-related changes in resiliencies to physical stressors in humans. Resilience is defined here as the dynamic ability to maintain or recover appropriate function in response to a physical stressor. For the purposes of this FOA, examples of physical stressors include hip fracture, infections, or surgical procedures. Examples of specific resiliencies include recovery of ambulation after a hip fracture, healing of incisional wounds, maintenance or recovery of hematopoietic function after cancer chemotherapy, or maintenance of cognitive function following general anesthesia. A phased innovation cooperative agreement mechanism involving an interdisciplinary research team will be used to support a single project on a limited number of important specific human physical resilience phenotypes (applicants are strongly encouraged not to exceed four). Learn more. Applications due: November 3, 2016, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on this date.

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